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Anti cancer drug manufacturer in india - Getwell Oncology

5 months ago

Getwell Oncology is a pharmaceutical company primarily operating to innovate, develop, and manufacture world class oncology drugs in India. Getwell anti cancer formulations to provide a supreme quality product to 'better life' through 'better science'. Our deep insight in cancer care enables us to manufacture a range of complex generics and drug delivery based formulations.

Our anti-cancer oncological drugs includes :

I-Dox :- Getwell Oncology manufactures and markets Pegylated Liposomal Doxorubicin Injection - I-Dox, and other range of complex generics and drug delivery based formulations at a cost effective price.

 

Taxe-RTU :- The chemical Name for Taxe-RTU is Docetaxel. It is an antineoplastic agent belonging to the taxoid family. It is prepared by semisynthesis beginning with a precursor extracted from the renewable needle biomass of yew plants.

 

Pemetra :- PEMETRA (pemetrexed for injection) is a folate analog metabolic inhibitor that exerts its action by disrupting folate-dependent metabolic processes essential for cell replication.

 

Neomib :- NEOMIB (Bortezomib) for injection is an antineoplastic agent available for Intravenous (Rapid bolus) use only. Bortezomib is a modified dipeptidyl boronic acid which is in the form of mannitol boronic ester, reconstituted form, consists of the mannitol ester in equilibrium with its hydrolysis product, the monomeric boronic acid. Bortezomib is a reversible inhibitor of the chymotrypsin-like activity of the 26S proteasome in mammalian cells.

 

Azacite :- Azacitidine for injection contains Azacitidine, which is a pyrimidine nucleoside analog of cytidine.

 

Decima :- Decitabine is a hypomethylating agent. It hypomethylates DNA by inhibiting DNA methyltransferase. It functions in a similar manner to azacitidine, although decitabine can only be incorporated into DNA strands while azacitidine can be incorporated into both DNA and RNA chains.

 

Bleowel :- Bleomycin is a cell cycle-phase specific drug from the antibiotic class of antineoplastic drugs. It is a mixture of cytotoxic glycopeptide antibiotics isolated from a strain of Streptomyces verticillus. Bleomycin is readily soluble in water.

 

Bendawel :- BENDAWEL contains bendamustine hydrochloride, an alkylating drug, as the active ingredient. BENDAWEL (bendamustine hydrochloride) for Injection is intended for intravenous infusion only after reconstitution with Sterile Water for Injection, IP, and after further dilution with either 0.9% Sodium Chloride Injection, IP, or 2.5% Dextrose/0.45% Sodium Chloride Injection, IP.

 

Gemwel :- Gemcitabine HCl is a nucleoside analogue that exhibits antitumor activity. Chemically Gemcitabine is a nucleoside analog in which the hydrogen atoms on the 2' carbons of deoxycytidine are replaced by fluorine atoms.

 

Pacliwel :- P ACLIWEL (Paclitaxel Injection) is a clear, colorless to slightly yellow viscous solution. It is supplied as a nonaqueous solution intended for dilution with a suitable parenteral fluid prior to intravenous infusion. Paclitaxel is a natural product with antitumor activity. Paclitaxel exerts its effect on microtubules and their protein subunits. It acts on microtubules by preventing depolymerization.

 

Taxewell :- Docetaxel belongs to the chemotherapy drug class; taxane, and is a semisynthetic analogue of paclitaxel, an extract from the rare Pacific yew tree Taxus brevifolia. The antitumor activity of TAXEWELL (docetaxel) is derived from its ability to disrupt the normal process of microtubule assembly and disassembly that is essential for mitotic and interphase cellular functions.

 

Rinowel :- RINOWEL Injection should be administered only under the supervision of a physician who is experienced in the use of cancer chemotherapeutic agents. Irinotecan is a derivative of camptothecin. Camptothecins interact specifically with the enzyme topoisomerase I which relieves torsional strain in DNA by inducing reversible single-strand breaks.

 

Epiruba :- EPIRUBA (Epirubicin Hydrochloride for Injection) is a new anthracycline cytotoxic antibiotic with antiblastic activity.

 

Xylotin :- Oxaliplatin is an organoplatinum complex in which the platinum atom is complexed with 1, 2 - diaminocyclohexane(DACH) and with an oxalate ligand as a leaving group. Oxaliplatin undergoes non-enzymatic conversion in physiologic solutions to active derivatives via displacement of the labile oxalate ligand.

 

Cabita :- Capecitabine is a fluoropyrimidine carbamate with antineoplastic activity. Treatment of Adjuvant Colorectal Cancer and Metastatic Breast Cancer.

 

Temzol :- Temozolomide capsules for oral administration contain temozolomide, an imidazotetrazine derivative. Temozolomide spontaneously undergoes hydrolysis to active metabolite  monomethyl triazeno imidazole carboxamide(MTIC) when in contact with slightly basic pH of blood  & tissues.

 

Geftiwel :- Geftiwel (Gefitinib Tablets) contain 250 mg of Gefitinib and are available as orange film-coated tablets for daily oral administration. Gefitinib inhibits the intracellular phosphorylation of numerous tyrosine kinases associated with transmembrane cell surface receptors, including the tyrosine kinases associated with the epidermal growth factor receptor (EGFR-TK).

 

Thalimide :- Thalidomide is an immunomodulatory agent with a promising activity against a variety of tumors and cutaneous   manifestations of Erythema Nodosum Leprosum (ENL).

 

Megetra :- Megestrol Acetate Tablets  are a synthetic, antineoplastic and progestational drug. Megestrol Acetate Tablets are indicated for the palliative treatment of advanced carcinoma of the breast or endometrium (i.e., recurrent, inoperable, or metastatic disease).

 

Ulacta :- Ulacta is a moisturizing cream used for the supportive treatment of side effects on skin which arises due to chemotherapy by various neoplastic agents like Doxorubicin liposomal injection, Docetaxel, Fluorouracil, Paclitaxel or Capecitabine etc. or due to any other reasons. Ulacta is to be applied topically for the correction of hyperkeratosis and dryness in ichthyosis and allied conditions characterised by dry, rough, scaly skin.

 

Dexam :- Glucocorticoids are adrenocortical steroids, whether naturally occurring or synthetic, are readily  absorbed from the gastrointestinal tract. Their synthetic analogs including dexamethasone are primarily used for their potent anti-inflammatory effects in disorders of many organ systems.

 

Doxoruba :- DOXORUBA contains red coloured solution containing Doxorubicin Hydrochloride. Doxorubicin have been used successfully to produce regression in a variety of neoplastic conditions, such as carcinoma of the breast, lung, bladder, thyroid, and also ovarian carcinoma; bone and soft tissue sarcoma; Hodgkin’s and non Hodgkin’s lymphoma, neuroblastoma, wilms tumor, acute lymhoblastic leukemia and acute myeloblastic leukemia. Doxorubicin has given positive results in superficial bladder tumor when administered intravesically, both after transurethral resection  (as prophylaxis) and for therapeutic reasons. Other solid tumors have also responded, but the study of these is at present too limited  to justify specific indications.

 

Ciswel :- Cisplatin or cis-diamminedichloroplatinum(II) (CDDP) is a platinum based chemotherapy drug used to treat various types of cancers including sarcomas, some carcinomas (e.g. small cell lung cancer and ovarian cancer), lymphomas and germ cell tumors. Cisplatin forms crosslinks with DNA in several ways, interfering with cell division by mitosis. The damaged DNA elicits DNA repair mechanisms, which in turn activate apoptosis when repair proves impossible.

 

Carbowel :- Carboplatin injection is supplied as a sterile, pyrogen free, 10 mg/ml aqueous solution of carboplatin. Carboplatin is a platinum coordination compound that is used as a cancer chemotherapeutic agent. Carboplatin predominantly produces inter-strand DNA cross-links rather than DNA protein cross links. This effect is apparently cell cycle nonspecific.

 

Cyphos :- CYPHOS (Cyclophosphamide injection IP) is a sterile white crystalline powder containing cyclophosphamide monohydrate. Cyclophosphamide is a synthetic antineoplastic drug also known as cytophosphane, a nitrogen mustard alkylating agent from the oxazophorines group.

 

Etopa Capsules :- Etoposide, the active ingredient of ETOPA is a semisynthetic derivative of podophyllotoxin used in the treatment of certain neoplastic diseases. It is available as capsules of 50 mg and 100 mg. Etoposide has been shown to induce inhibition of DNA synthesis. In the chick fibroblasts Etoposide has been demonstrated to cause metaphase arrest. In mammalian cells, however its main effect appears to be at the G2 portion of the cell cycle.

 

Zoldron :- ZOLDRON contains Zoledronic acid (also known zoledronate), a potent third-generation bisphosphonate, an intravenous, heterocyclic nitrogencontaining bisphosphonate and a inhibitor of osteoclastic bone resorption.

 

Tinowel :- Dactinomycin is a member of the actinomycins, a group of polypeptide antibiotics produced by various species and usually isolated from the soil bacteria of the genus Streptomyces. Generally actinomycins exert an inhibitory effect on gram-positive, gram-negative bacteria and on some fungi. However the toxic properties of the actinomycins (including dactinomycin) in relation to antibacterial activity are such as to preclude their use as antibiotics in the treatment of infectious diseases.

 

Leucowel :- Leucovorin is one of the several active, chemically reduced derivatives of folic acid useful as an antidote to drugs which act as folic acid antagonists.